" ...biophotonics [is becoming] a field that will drive the discovery of new principles of cellular and molecular biology."

- 2004, Nature Reviews Molecular and Cellular Biology

The McMaster Biophotonic Imaging Facility is slated for completion in Fall, 2005 within the Department of Biochemistry and Biomedical Sciences in the McMaster Health Sciences Centre. This is a regional imaging facility dedicated to live cell fluorescence microscopy with a large variety of microscopes and techniques:

Two-photon Confocal Microscopy

Wide-Field 3D Deconvolution Microscopy

High resolution bacterial imaging

Multi-color Aequoria Flourescent Protein imaging

Fluorescence Lifetime Imaging (FLIM) and Fluorescent Resonant Energy Tranfer (FRET)

Fluorescence Intensity Distribution analysis (FIDA)

Fluorescence Recovery After Photobleaching (FRAP) and Photo-Activation (PA)

High Content Screening (HCS) fluorescent microscopy

Live cell three and four + dimensional imaging

Fluorescence Correlation Spectroscopy (FCS)

High-speed Intravital fluorescence Imaging

The facility will also include devices for spectrometry and plate reading. Housed in the same space will be biosafety level 2 HEPA hoods and tissue culture incubators for full cell culture in close proximity to the imaging equipment. Most devices will have live cell capability. We will have an on-site technician for advice and training on most devices.

For more information, contact:

Dr. David W. Andrews or Dr. Ray Truant.

Supported by: