|Martin Gibala, PhD|
Professor and Chair
Location: Ivor Wynne Centre, Room 210
My research examines the regulation of skeletal muscle energy provision. I am particularly interested in the potential for exercise and/or nutrition to induce metabolic adaptations at the molecular and cellular levels in humans. In addition to basic, mechanistic studies, I also conduct applied research that examines the impact of exercise training and dietary manipulation on sport performance. Recent work in my laboratory has focused on two main areas:
(1) Metabolic adaptations to low-volume, high-intensity interval training, with an emphasis on the regulation of oxidative energy provision.
(2) The potential for alterations in nutrient availability to impact the acute or chronic adaptations to exercise training.
(names of students supervised are underlined)
Gillen JB, Percival ME, Ludski A, Tarnopolsky M, Gibala MJ. Interval training in the fed or fasted state improves body composition and muscle oxidative capacity in overweight women. Obesity. 2013 Feb 1. Epub ahead of print [PMID: 23723099]
Tjønna AE, Leinan IM, Bartnes AT, Jenssen BM, Gibala MJ, Winett RA, Wisløff U. Low- and high-volume of intensive endurance training significantly improves maximal oxygen uptake after 10-weeks of training in healthy men. PLOS ONE 2013 May 29;8(5):e65382. [PMID: 23734250].
Gibala MJ. Nutritional strategies to support adaptation to high-intensity interval training in team sports. In: Nutritional Coaching Strategy to Modulate Training Efficiency, edited by Tipton KD, van Loon LJC. Nestec Ltd, Vevey / S. Karger AG: Basel. Nestle Nutr Inst Workshop Ser. 75:41-49, 2013. [PMID: 23765349]
Gibala MJ, Little JP, MacDonald MJ, Hawley JA. Physiological adaptations to low-volume, high-intensity interval training in health and disease. J Physiol 590: 1077-1084, 2012. [PMID: 22289907]
Cermak NM, Noseworthy MD, Bourgeois JM, Tarnopolsky MA, Gibala MJ. Diffusion tensor MRI to assess skeletal muscle disruption following eccentric exercise. Muscle and Nerve 46:42-50, 2012. [PMID: 22644795]
Gillen JB, Little JP, Punthakee Z, Tarnopolsky MA, Riddell MC, Gibala MJ. Acute high-intensity interval exercise reduces the postprandial glucose response and prevalence of hyperglycemia in patients with type 2 diabetes. Diabetes Obes Metab 14:575-77, 2012.
Little JP, Gillen JB, Percival M, Safdar A, Tarnopolsky MA, Punthakee Z, Jung ME, Gibala MJ. Low-volume high-intensity interval training reduces hyperglycemia and increases muscle mitochondrial capacity in patients with type 2 diabetes. J Appl Physiol 111:1554-1560, 2011. [PMID: 21868679]
Little JP, Safdar A, Bishop D, Tarnopolsky MA, Gibala MJ. An acute bout of high-intensity interval training increases the nuclear abundance of PGC-1? and activates mitochondrial biogenesis in human skeletal muscle. Am J Physiol Reg Integr Comp. 300:R1303-1310, 2011. [PMID: 21451146]
Cochran AJC, Little JP, Tarnopolsky MA, Gibala MJ. Carbohydrate feeding during recovery alters the skeletal muscle metabolic response to repeated sessions of high-intensity interval exercise in humans. J Appl Physiol. 108:628-636, 2010. [PMID: 20056852]
Little JP, Safdar AS, Wilkin GP, Tarnopolsky MA, Gibala MJ. A practical model of low-volume high-intensity interval training induces mitochondrial biogenesis in human skeletal muscle: potential mechanisms. J Physiol. 586: 1011-1022, 2010. [PMID: 20100740]