| David R. Chettle |
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Professor, Medical Physics & Applied Radiation Sciences
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Research InterestsResearch Interests Human body composition. Development of methods to measure elemental content in living human subjects. Examples include lead (Pb) in bone using x-ray fluorescence, strontium in bone using x-ray fluorescence, aluminum in bone using neutron activation, mercury in kidney or other sites using x-ray fluorescence, manganese in bone using neutron activation, nitrogen (protein) in whole body using prompt gamma neutron activation, potassium (body cell mass) by whole body counting, cadmium in liver or kidney by prompt gamma neutron activation, possible use of lanthanides with high neutron capture cross sections as “nuclear medicine” tracers. Interaction of science and faith, science and religion dialogue. PublicationsRecent Publications C.M. Heirwegh, D.R. Chettle, A. Pejovic-Milic, “Evaluation of imaging technologies to correct for photon attenuation in the overlying tissue for in vivo bone strontium measurements” Physics in Medicine and Biology 55, 1083-1098, 2010. Ana Pejovic-Milic, Aslam, David R. Chettle, John Oudyk, Michael W. Pysklywec, Ted Haines, “Bone manganese as a biomarker of manganese exposure: A feasibility study” American Journal of Industrial Medicine 52 742-750, 2009. Aslam, K. Davis, A. Pejovic Milic, D.R. Chettle, “Non Invasive Measurement of Aluminium in Human Bone: Preliminary Human Study and Improved System Performance” Journal of Inorganic Biochemistry 103, (sp. iss.) 1585-1590, 2009. M. Zamburlini, J. Campbell, G. De Silveira, R. Butler, A. Pejovic Milic, D.R. Chettle, “Strontium depth distribution in human bone measured by micro-PIXE” X-Ray Spectrometry, 38, 271-277, 2009. J.A.A. de Brito, M.L. de Carvalho, D.R. Chettle, “Calibration of 109Cd KXRF systems for in vivo bone lead measurements: the guiding role of assumptions for least-squares regression in practical problem solving” Physics in Medicine and Biology, 54, 919-934, 2009. Students SupervisedStudents Supervised
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