The Institute supports four Centres currently, providing the opportunity for cross fertilization among the Centres each with its own experimental and development goals and all sharing the common vision. Other Centres will be introduced as the Institute develops.

The Institute also houses the Mobix Lab, a central facility that provides molecular biology expertise and services to the research community, both inside and outside McMaster.

Antimicrobial Research Centre
The field of infectious disease and antimicrobial therapy is being transformed at present by the growing availability of the complete genome sequences for several microbes including bacteria, fungi and protists. This information will drive the research of this Centre in the area of infectious diseases for the next several decades.

Centre for Gene Therapeutics
The mission of this Centre is to investigate, create and implement approaches utilizing the delivery of genes as therapeutic agents in the treatment of human and animal disease. This entails basic investigations to target gene product involvement, creation of vector systems for appropriate delivery of therapeutic genes and rapid translation of promising medicines to the clinical setting.

Centre for Evolutionary and Genomics Biotechnology(CEGeBio)
The mission of the Centre for Evolutionary and Genomics Biotechnology (CEGeBio) is to provide automated tools to the study of environmental, evolutionary and genomics issues with the aid of modern biotechnology tools. With high throughput instruments, research in these fields can be accomplished at a faster rate, in greater depth and with greater precision. With these instruments we can analyze the consequences of and the changes in gene expression in organisms as a response changes within the environment. The purpose of the centre is to bring the power of the technologically revolutionary methods of genomics to bear on important environmental problems in biology.

Functional Genomics Centre
The field of functional genomics seeks to define the biochemical and biological functions of the protein products of genes on a genome-wide scale. The mission of the Centre is to develop new technologies and to exploit recent advances in gene expression profiling, bioinformatics and proteomics to discover gene function and to integrate this knowledge into genetic pathways that regulate organismal development and physiology. A major focus of our research is to use functional genomic technologies to identify new genetic markers and molecular therapeutic targets associated with human diseases.