Office: Juravinski Cancer Centre, room 4-29
Phone: (905) 387-9711 ext. 67145
Deformable gel dosimeters for radiation therapy
My interest in this field is two-fold: first, the primary focus is on the development of new radiochromic materials for use in radiation therapy dosimetry and developing optical techniques to read them; second, applying gel dosimetry to answer questions in radiation therapy, especially where organ motion and deformation are considered.
Development of poly(vinyl alcohol) cryogels to mimic the optical properties of tissues
Biophotonics is an emerging field in biological sciences that uses light to study tissue. Advances in this field will benefit from realistic models that mimic the mechanical and optical properties of body tissues. At present, very simple models are used to test new technologies prior to using them on living subjects. This program seeks to develop new optical materials that address the need for better tissue models to support further technology development in biophotonics. The mechanical and optical properties of poly(vinyl alcohol) cryogels (PVA-C) are well suited to this task. The product of this research will be an anatomically and optically correct model of a male pelvis. The primary end use of this model is in the field of photodynamic therapy; however, due to the material's tissue equivalence, other anticipated uses are in the field of radiation therapy for prostate cancer.
Diagnostic and therapeutic applications of light
My research background is in the field of photodynamic therapy dosimetry and tissue optics, especially as they apply to cancer. Current research activities include the development of a photo immunotherapy technique for the treatment of melanoma.
M.M. Eyadeh, M.A. Weston, J. Juhasz, K.R. Diamond, "Translucent poly (vinyl alcohol) cryogel dosimeters for simultaneous dose buildup and monitoring during chest wall radiation therapy", Journal of Applied Clinical Medical Physics, 17(5), 2016.
K. Malkoske, M. Nielsen, E. Brown, K. Diamond, N. Freniere, J. Grant et al., "Sci-Fri AM: Quality, Safety and Professional Issues 02: Reent work on TQC suite and data from a National survey on community uptake" Medical Physics, 43(8), 4952-4953, 2016.
A. Mallawi, T.T. Farrell, K.R.Diamond, M. Wierzbicki, "Poster-32: Atlas selection for automated segmentation of pelvic CT for prostate radiotherapy" Medical Physics 43(8), 4943-4943, 2016.
J.P. Bissonnette, L. Tantot, K. Diamond, E. Villarreal-Barajas, J. Grant, et al., "Technical Quality Control Guidelines for Canadian Radiation Treatment Centres" Canadian Partnership for Quality Radiotherapy, TCQ.2016.05.01, 2016.
SCA Yeh, CSN Ling, DW Andrews, MS Patterson, KR Diamond,et al., "5-aminolevulinic acid for quantitative seek-and-treat of high-grade dysplasia in Barrett’s esophagus cellular models" Journal of biomedical optics 20 (2), 028002-028002, 2016.
MM Eyadeh, TJ Farrell, KR Diamond, "Evaluation of a ferrous benzoic xylenol orange transparent PVA cryogel radiochromic dosimeter" Physics in Medicine and Biology 59 (7), 1773, 2016.
J Pekar, KR Diamond, "Poster—Thur Eve—10: Long term stability of VMAT quality assurance parameters using an EPID" Medical Physics 39 (7), 4626-4626, 2012.
O Dona, K Diamond, O Ostapiak, M Wierzbicki, "Poster—Thur Eve—28: Optimization of a prostate cancer IGRT protocol" Medical Physics 39 (7), 4629-4630, 2012.
SCA Yeh, KR Diamond, MS Patterson, Z Nie, JE Hayward, Q Fang, "Monitoring photosensitizer uptake using two photon fluorescence lifetime imaging microscopy" Theranostics 2 (9), 817-826, 2012.
KR Diamond, MS Patterson, TJ Farrell, "Quantification of fluorophore concentration in tissue-simulating media by fluorescence measurements with a single optical fiber" Applied optics 42 (13), 2436-2442, 2003.
R Weersink, MS Patterson, K Diamond, S Silver, N Padgett, "Noninvasive measurement of fluorophore concentration in turbid media with a simple fluorescence/reflectance ratio technique " Applied optics 40 (34), 6389-6395, 2001.
RA Weersink, JE Hayward, KR Diamond, MS Patterson, "Accuracy of noninvasive in vivo measurements of photosensitizer uptake based on a diffusion model of reflectance spectroscopy" Photochemistry and photobiology 66 (3), 326-335, 1997.
Current Graduate Students
Peter Fiee, PhD (Medical Physics)
Hailah Rashed, MSc (Medical Physics)
Former Graduate Students
Molham Eyadeh, PhD (Medical Physics), 2016
George Counter (Medical Physics)
Former Undergraduate Students
- MedPhys 772: Medical Health Physics (non-ionizing radiation)